MULTIPLE-OMICS ANALYSIS OF AGGREPHAGY-RELATED CELLULAR PATTERNS AND DEVELOPMENT OF AN AGGREPHAGY-RELATED SIGNATURE FOR HEPATOCELLULAR CARCINOMA

Multiple-omics analysis of aggrephagy-related cellular patterns and development of an aggrephagy-related signature for hepatocellular carcinoma

Abstract Background Protein aggrephagy, a selected autophagy process response for degrading protein aggregates, plays a critical role in various cancers.However, its regulatory mechanisms and clinical implications in hepatocellular carcinoma (HCC) remain largely unexplored.Methods We integrated bulk RNA-seq data from TCGA and single-cell RNA sequen

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Blink reflex changes and sensory perception in infraorbital nerve-innervated areas following zygomaticomaxillary complex fractures

Background Infraorbital nerve dysfunction is commonly reported after zygomaticomaxillary complex fractures.We evaluated sensory changes in four designated areas (eyelid, iPhone XS nose, zygoma, and lip) innervated by the infraorbital nerve.This evaluation was conducted using the static two-point discrimination test and the vibration threshold test.

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